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A RECENT DEVELOPMENTS IN THE USE OF INTRALESIONAL INJECTIONS KELOID TREATMENT

Mr. Ashish Siddheshwarappa Ghodki, Prof. Abhijeet R. Shete, Dr. Megha T. Salve

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Paper Contents

Abstract

Keloid scars are frequently seen as unsightly and annoying issues that develop after traumas. They may impair joint mobility and result in discomfort, irritation, pain, functional and aesthetic abnormalities, and psychological stress. A worse quality of life and decreased functional performance are the eventual outcomes of these variables working together. Both surgical and non-surgical techniques have been used to improve keloid scars. Finding a uniform therapy that may produce the best outcomes for all kinds of scars has been difficult, though. We examined the majority of the literature on intralesional injection treatment of hypertrophic scars and keloids using a PubMed search, highlighting both existing (corticosteroid, 5-fluorouracil, bleomycin, interferon, cryotherapy, and verapamil) and upcoming (interleukin-10 and botulinum toxin type A) treatments. Additionally, the retrieved papersreference lists were examined. Pathological scars known as keloids appear as nodular lesions that spread beyond the site of damage. They frequently keep growing over time rather than regressing on their own. The absence of regulatory systems that self-regulate cell proliferation and tissue repair leads to the aberrant wound-healing process that underlies keloid development. Keloids may cause functional disability, cosmetic deformity, and a decline in quality of life.

Copyright

Copyright © 2025 Mr. Ashish Siddheshwarappa Ghodki, Prof. Abhijeet R. Shete, Dr. Megha T. Salve. This is an open access article distributed under the Creative Commons Attribution License.

Paper Details
Paper ID: IJPREMS51100056816
ISSN: 2321-9653
Publisher: ijprems
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