Paper Contents
Abstract
Alzheimers disease (AD) is a progressive and irreversible neurodegenerative disorder characterized by memory loss, cognitive impairment, and behavioral abnormalities. Affecting millions worldwide, it places a major burden on patients, families, and healthcare systems. The complex pathology of AD includes -amyloid plaques, tau protein hyperphosphorylation, synaptic dysfunction, oxidative stress, and chronic neuroinflammation. Current treatments primarily offer symptomatic relief but fail to halt or reverse disease progression. In recent years, significant advancements have emerged involving monoclonal antibodies, gene-modifying therapies, stem cell interventions, nanomedicine, and multi-target drug approaches. This review highlights the current pharmacological therapies and explores promising new strategies under investigation for more effective management of Alzheimers disease.
Copyright
Copyright © 2025 SHAIKH SUFIYAN AHEAMD, SANDIP W PATIL, BHURE ANUJA, SHAIKH UZER, RAJPUR KALAYANI, JADHAV DURGESH. This is an open access article distributed under the Creative Commons Attribution License.
