Paper Contents
Abstract
Lansoprazole, a proton pump asset( PPI), is extensively used for the treatment of acid- related diseases similar as gastroesophageal influx complaint( GERD), peptic ulcer complaint, and Zollinger- Ellison pattern. The ideal of the present study was to formulate and estimate Lansoprazole tablets using suitable excipients to insure stability, effective medicine release, and patient compliance. Due to the acid- labile nature of Lansoprazole, expression strategies concentrated on enteric coating and pH-sensitive polymers to cover the medicine from gastric declination and grease targeted intestinal release. The tablets were prepared using the direct contraction system and subordinated topre-compression andpost-compression evaluations including hardness, frangibility, decomposition time, medicine content uniformity, and in vitro medicine release studies. Results demonstrated satisfactory physicochemical parcels and harmonious medicine release in dissembled intestinal fluid, attesting the effectiveness of the expression. The optimized batch showed controlled and predictable release characteristics, making it suitable for clinical operation. This study highlights the significance of expression ways in enhancing the stability and remedial efficacity of acid-sensitive medicines like Lansoprazole.
Copyright
Copyright © 2025 Mr.Karad Yogesh Babasaheb . This is an open access article distributed under the Creative Commons Attribution License.
