Paper Contents
Abstract
AbstractThe present work describes the formulation and evaluation activated of an ophthalmic delivery system of an anti-bacterial agent- Moxifloxacin. Sodium alginate was used as the gelling agent for Ion activated in situ gel, Polyacrylic acid (Carbopol- 934) was used as the gelling agent for pH-triggered in situ gel and Poloxamer was used as the gelling agent for temperature activated in situ gel in combination with HPMC K4 M which acted as a viscosity enhancing agent. The evaluated for determination of visual appearance, clarity, pH and Drug Content, In vitro gelation studies, Rheological studies, In vitro drug release study, antimicrobial efficacy Studies, Ocular irritation studies, Sterility testing, Stability studies. Cumulative percent release of 86.89 %, 63.23 % and 76.37 %, was observed for optimized formulations
Copyright
Copyright © 2025 Sachin Vilas wagh . This is an open access article distributed under the Creative Commons Attribution License.
