Paper Contents
Abstract
From the first natural product isolation to its current applications in structure-based drug design, medicinal chemistry has always played a crucial role in drug discovery. Thanks to developments in computational chemistry, artificial intelligence (AI), and high-throughput screening, drug design is now more precise and effective than before. The perseverance of medicinal chemists and the development of small-molecule approaches through trial and error have enabled these breakthroughs. AI-driven molecular docking and in silico modeling, along with other techniques like automated synthesis and sustainable chemistry, are examples of how modern medicine integrates chemistry, biology, and data science. To speed up the drug development process, the role has expanded beyond traditional synthesis to involve interdisciplinary partnerships with pharmacologists, bioinformaticians, and medical specialists. This article discusses medicinal chemistry's historical contributions, notable developments in the field, and the field's prospects in the age of targeted medications and more individualized treatment.
Copyright
Copyright © 2025 Rashmi Kotwal. This is an open access article distributed under the Creative Commons Attribution License.
