Paper Contents
Abstract
Malarial coma, a severe and often fatal complication of Plasmodium falciparum infection, remains a major public health challenge, particularly in malaria-endemic regions. While factors like healthcare access and environmental conditions play a role, genetics has emerged as a critical factor in determining why some individuals develop severe malaria, including malarial coma, while others do not. This article explores the genetic factors that influence susceptibility to malarial coma, examines the epidemiology of the disease, and discusses the clinical implications of these findings. By integrating epidemiological data, genetic research, and clinical insights, this review aims to provide a comprehensive understanding of malarial coma and its underlying mechanisms.
Copyright
Copyright © 2025 Anish Subhash Pashte, Turusbekova Akshoola Kozmanbetovna, Parpieva Takhmina Makhamatkalylovna, Vaibhav Pagare. This is an open access article distributed under the Creative Commons Attribution License.
