Paper Contents
Abstract
The gut microbiome, a complex and dynamic ecosystem residing within the gastrointestinal tract, has emerged as a critical player in shaping host health and susceptibility to disease. Beyond its well-recognized roles in nutrient metabolism and immune system development, accumulating evidence highlights the profound influence of the gut microbiome in infectious diseases. This review explores the multifaceted mechanisms by which the gut microbiome interacts with pathogens, influencing infection susceptibility, severity, and outcomes. We delve into the implications of microbiome dysbiosis in various infectious disease contexts, ranging from bacterial and viral to fungal and parasitic infections. Furthermore, we discuss the therapeutic potential of targeting the gut microbiome through strategies such as fecal microbiota transplantation, probiotics, prebiotics, and phage therapy to prevent and treat infectious diseases. Understanding the intricate interplay between the gut microbiome and infectious agents is crucial for developing novel and effective approaches to combat infectious diseases and improve global health.
Copyright
Copyright © 2025 Janmejay Soni. This is an open access article distributed under the Creative Commons Attribution License.
