Paper Contents
Abstract
Aim of the present study was to develop the Fast-Dissolving Oral flicks of Glipizide. It's alternate- generation sulfonylurea that can acutely lower the blood glucose position. Fast dissolving oral flicks deliver medicine directly in the vascular system and bypasses the hepatic first pass metabolism so cure of the medicine may also reduce significantly. Fast dissolving flicks were prepared using solvent casting system, hydrophilic polymers (HPMC K- 15, HPMCE-15, HPMC K- 100) were named as film forming agents and cut- 400 was used as plasticizer to give inflexibility to the flicks. In FT- IR study no commerce was observed between medicine and the excipients. Three blank flicks were named for the objectification of medicine. After characterization the medicine loaded flicks and studying their decomposition time & in- vitr medicine release studies, among them was named the stylish expression as its decomposition and dissolution time was less and it releases medicine to a lesser extent from 93 to further than 100 in ten twinkles. expression was named stylish expression as its decomposition and dissolution time was less and it released medicine to a lesser extent compared to other phrasings. thus, presto dissolving oral flicks can play an important part in oral medicine delivery. Drug loaded flicks with both the polymers were stable under 40 C 75 RH conditions.
Copyright
Copyright © 2025 Aditya Ashok Bahir. This is an open access article distributed under the Creative Commons Attribution License.
