Paper Contents
Abstract
Darunavir, also known as TMC114 in pharmaceutical terminology, is a second-generation protease inhibitor used to treat human immunodeficiency virus. Synthetic non-peptide protease inhibitor Darunavir has demonstrated remarkable potency against wild-type HIV and is a key component of highly active antiretroviral therapy (HAART), which is regarded as a major advancement in HIV therapy. Various analytical methods have been established for the determination of Darunavir in the pharmaceutical dosage form and bulk form. For Darunavir, methods for impurity profiling and human plasma stability are also discussed. These analytical techniques can be applied to the qualitative and quantitative determination of Darunavir as well as to the related degradants in bulk formulations and biological fluids. The paper that follows reviews analytical techniques, one of which is the estimation of antiretroviral medications.
Copyright
Copyright © 2024 R SWETHA SRI. This is an open access article distributed under the Creative Commons Attribution License.
