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AN OVERVIEW OF AZOLE ANTIFUNGALS

Varsha B. Ghongade B. Ghongade, Ashwini Andhale, Santosh Waghmare, DR. Hament Kamble , Ashwini Andhale , Santosh Waghmare , DR. Hament Kamble

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Abstract

As the number of individuals with immune system suppression has grown in recent years, the danger of human fungal infections has significantly increased. Fortunately, there has been a rapid advancement in the treatment of fungal infections. It was discovered that combining already available azoles with additional antifungals is probably going to increase their efficacy. But after receiving antifungal medication, a number of circumstances might cause therapeutic failure or recurrence. These variables relate to the various properties of the antifungal(s) employed. Therefore, professionals should thoroughly research the various properties of antifungals in order to prevent these issues and further to make the best use of the antifungals.The goal of the current study was to identify variations in the pharmacology, pharmacokinetics, spectrum of activity, toxicity, and possible medication interactions of the related azoles.The azoles of interest are sufficiently diverse in terms of their pharmacology, pharmacokinetics, spectrum of activity, safety, toxicity, and potential drug interactions, according to the current review, which enables medical professionals to distinguish between these agents based on their individual properties when designing a patient's therapy.

Copyright

Copyright © 2023 Varsha B. Ghongade, Ashwini Andhale, Santosh Waghmare, DR. Hament Kamble . This is an open access article distributed under the Creative Commons Attribution License.

Paper Details
Paper ID: IJPREMS30800002397
ISSN: 2321-9653
Publisher: ijprems
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