Clinical Trial Registries and Reporting: Progress, Pitfalls, and Path Forward
Kunchala Murali Manohar Joshi Murali Manohar Joshi
Paper Contents
Abstract
Abstract: Clinical trial registries are becoming a vital resource for advancing ethical integrity, accountability, and openness in scientific research. Clinical trial outcomes have historically been selectively published and underreported, undermining public confidence and scientific integrity. A crucial step in enhancing trial information accessibility and guaranteeing that trials are prospectively registered and publicly available was the creation of registries like ClinicalTrials.gov, EudraCT, and the Clinical Trials RegistryIndia (CTRI). Despite these advances, challenges persist in maintaining data quality. harmonization, and interoperability across registries. Variations in data fields, reporting standards, and compliance mechanisms among national and regional databases continue to hinder global consistency. Despite these advances, challenges persist in maintaining data quality. harmonization, and interoperability across registries. Variations in data fields, reporting standards, and compliance mechanisms among national and regional databases continue to hinder global consistency.
Copyright
Copyright © 2025 Kunchala Murali Manohar Joshi. This is an open access article distributed under the Creative Commons Attribution License.