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Development and optimization of fenugreek extract loaded nanoemugel for the treatment Anti-inflammatory Activity

Roshanee dipak agrawal dipak agrawal

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Abstract

Abstract The bright green clover-like leaves of fenugreek (Trigonella foenum graceum) have a pleasantly bitter-sweet flavour. These seeds are quite hard and are usually ground into a powder. Their flavour is typically compared to maple syrup. The seeds have a flavour that is remarkably similar to the leaves. For transdermal distribution of Trigonella foenum graceum extract, a nanoemulsion system was designed with Tween 80 as the surfactant, IPA as the co-surfactant, and Isopropyl myristate as the oil phase. In the pseudo-ternary phase diagram generated at various Tween 80, a region of nanoemulsion was discovered. Water (16.6%), Smix (75%), and Oil (8.3%) The gelling agent carbapol 934 was used to make a nanoemulsion-based gel. Quercetin absorption through the skin was shown to be faster in this nanoemulsion than in aqueous solution. The results imply that the WO nanoemulsion is a suitable anti-inflammatory gel because nanoemugel improves drug bioavailability.Key words: Nanoemulsion, Nanoemugel, Trigonella foenum graceum extract.

Copyright

Copyright © 2023 Roshanee dipak agrawal. This is an open access article distributed under the Creative Commons Attribution License.

Paper Details
Paper ID: IJPREMS31100002996
ISSN: 2321-9653
Publisher: ijprems
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