Paper Contents
Abstract
There is an undeniable interaction between the brain and the gut. This connection is referred to as the microbiota-gut-brain-axis (MGBA). This study was done to examine the levels of Enterobacter sp in stool samples and to determine its potential as a diagnostic tool for depression. Fifty individuals took part in the research. Random sampling method was employed, Patient Health Questionnaires (PHQ) were given out and consent forms were signed. Afterwards, fecal samples were collected from 50 individuals, of which 36 were patients diagnosed with depression and 14 were healthy individuals that served as control. In addition, the viable count of Enterobacter sp isolated from people with depression was significantly higher than that of the control group. The independent samples t-test showed that the mean viable count of Enterobacter sp in depressed subjects is significantly above that of the control subjects, with a mean difference of 0.9889, t9.083. Conversely, a high level of Enterobacter sp can be used as a biomarker for depression and other mood-related disorders.
Copyright
Copyright © 2024 Agu Kingsley. This is an open access article distributed under the Creative Commons Attribution License.
