Paper Contents
Abstract
In the present study evaluation of the anti-ulcer activity of Madhuca Indica Study was carried out, by using three methods i.e.,alcohol, paracetamol and stress induced ulcers in rats pretreated with the doses of 250 mgkg AQSMI and ALMI, 10mgkg Omeprazole and 50mgkg Ranitidine. To evaluate the anti ulcer activity of aqueous and alcoholic extracts of Madhuca Indica leaves (AQSMI and ALMI) at 250 doses using different experimentally induced gastric ulcer models in rats. In alcohol-induced ulcers, AQSMI and ALMI were effective in reducing lesion index and increasing the gastric mucus content. It was also effective in decreasing ulcer index in paracetamol induced ulcers. All the results obtained with Madhuca Indica were dose dependent. The results suggest that AQSMI and ALMI possesses significant and dose dependent anti ulcer activity. The anti ulcer activity of AQSMI and ALMI can be attributed to its cyto protective and anti secretory action.
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