Paper Contents
Abstract
Diabetes mellitus is a chronic metabolic disorder affecting carbohydrate metabolism. It has become a global health concern. Withania coagulans commonly known as "Paneer Dodi," holds significant promise in diabetes management. The present review explores the pharmacological potential of W. coagulans, emphasizing its traditional uses and diverse biological activities. The plant is rich in bioactive compounds like withanolides, demonstrates anti-diabetic, anti-inflammatory, antioxidant, and antimicrobial effects. Coagulins unique peptides derived from W. coagulans exhibit therapeutic potential. The plant's cultivation, chemical constituents and various types of diabetes are discussed. This overview underscores the relevance of W. coagulans in natural product-based drug discovery by providing insights into its diverse therapeutic applications. It explores the extraction methods, pharmacological actions, and therapeutic potential of Withania coagulans. Hydroalcoholic and hot water extraction processes are detailed with emphasizing factors affecting efficiency. The pharmacological actions encompass hepatoprotective, antihyperglycaemic, anti-inflammatory, anti-cancer, wound healing, anti-mutagenic, antibacterial, antihelmintic, cardiovascular, diuretic effects and potential applications in Alzheimer's disease. Withanolides play a pivotal role in its diverse therapeutic effects. The findings suggest Withania coagulans as a promising research and development of novel therapeutic agents. This succinctly captures the key aspects by providing a concise overview of Withania coagulansmultifaceted medicinal properties.
Copyright
Copyright © 2024 Tandale Chaitanya Popat. This is an open access article distributed under the Creative Commons Attribution License.
