Paper Contents
Abstract
Jamu, a traditional Indonesian herbal medicine, is composed of plant, animal, and mineral extracts, and has been used for generations. However, some slimming herbal products may contain synthetic pharmaceutical compounds, such as furosemide, sibutramine e hydrochloride, and hydrochlorothiazide, raising safety concerns. This study aimed to identify the medicinal chemicals in the slimming herbal products available in Medan City in 2024. A laboratory-based experimental method was employed, including both qualitative and quantitative analyses. The procedure involved preparing test solutions, comparator standards for sibutramine e hydrochloride and furosemide, and thin-layer chromatography (TLC) and UV-Vis spectrophotometry. Qualitative analysis showed that out of 10 samples, one tested positive for furosemide. Quantitative analysis at 358 nm revealed a furosemide concentration of 7.79% in Sample B. No None of the samples contained sibutramine e hydrochloride. These findings highlight the potential adulteration of herbal products with synthetic pharmaceuticals, emphasizing the need for stricter quality control and regulations to ensure consumer safety.
Copyright
Copyright © 2025 Putri Tri Hartini, Hendri Faisal, Indah Pertiwi, Meiva Amelia Lubis. This is an open access article distributed under the Creative Commons Attribution License.
