In-Silico and Ex-Vivo Analysis of Anti-Cancer Activity of Solasodine against Breast Cancer- A review
Karthika Devi S Devi S
Paper Contents
Abstract
Cancer kills almost millions of people per year. Fatal breast cancer can result in death. The early diagnosis of breast cancer and treatment can increase the survival rate. Breast cancer is the second most disease spreading worldwide. The pink ribbon day campaign focuses on creating acknowledgment among people about breast cancer. Chemotherapy can create adverse side effects and selective novel anticarcinogens are required to treat them. Solasodine obtained from medicinal plants helps in curing malignant skin cancer and several types of cancer. It mostly affects women above the age of 40. Solanum nigrum, also known as the poisonberry, involves various traditional treatments such as treating ringworm, bacterial infection, cough, and indigestion. Major components are glycoalkaloids, glycoproteins, and polysaccharides. The proliferation activity of the Solanum nigrum helps to fight against various tumor cell lines including HepG2, and HT29. MDA-MB-231 is a cell line that can induce cancer in the breast.
Copyright
Copyright © 2023 Karthika Devi S. This is an open access article distributed under the Creative Commons Attribution License.