Paper Contents
Abstract
Osseointegration, the direct structural and functional connection between living bone and an implant, has revolutionized dentistry, orthopedics, and prosthetic rehabilitation. The concept was accidentally discovered by Per-Ingvar Brnemark in 1952, when he observed that titanium fused irreversibly with bone. This led to the first successful dental implant placement in 1965, establishing the foundation for modern implantology. In the present era, osseointegration has been enhanced by advanced surface modifications, such as sandblasting, acid etching, nanocoatings, and bioactive materials, improving implant stability and reducing healing times. 3D imaging, guided surgery, and digital workflow integration have further refined implant placement and outcomes. Beyond dentistry, osseointegrated limb prostheses have provided amputees with superior mobility and quality of life.The future of osseointegration is driven by nanotechnology, smart biomaterials, tissue engineering, and artificial intelligence (AI). Bioactive coatings, stem cell therapy, and gene editing hold promise for accelerating bone integration and enhancing implant longevity. 3D printing and patient-specific implants are poised to improve customization and success rates, while AI-driven diagnostics and robotic-assisted surgeries will optimize treatment planning. In conclusion, osseointegration has evolved from a serendipitous discovery to a cornerstone of modern medicine, with future advancements set to further revolutionize regenerative therapies, implantology, and prosthetic integration.
Copyright
Copyright © 2025 DR.LAKSHMANA RAO. BATHALA. This is an open access article distributed under the Creative Commons Attribution License.
