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PHARMACOLOGICAL EVALUATION OF ANTI DEPRESSANT ACTIVITY OF CAESALPINIA PULCHERRIMA IN ANIMAL MODELS

Samreen

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Abstract

Caesalpinia pulcherrima belongs to the family fabaceae. Depressions are widespread psychiatric disorders affecting around 5% of the population. Furthermore, it is difficult to predict which patient will respond to any given treatment. In the traditional systems of medicine, many plants have been used to treat anxiety and depression for thousands of years. The present study was designed to evaluate the antidepressant activity of the alcoholic and aqueous extracts of Caesalpinia pulcherrima leaves in rodents. The antidepressant activity was tested by using forced swim test and Open Field Test. The results infer that reduced immobility time elicits antidepressant activity. It was concluded that alcoholic and aqueous extracts of Caesalpinia pulcherrima leaves having antidepressant activity. Alcoholic extract of Caesalpinia pulcherrima leaves showing more significant activity over the aqueous extract.

Copyright

Copyright © 2025 Samreen. This is an open access article distributed under the Creative Commons Attribution License.

Paper Details
Paper ID: IJPREMS50900028293
ISSN: 2321-9653
Publisher: ijprems
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