PHARMACOLOGICAL EVALUATION OF ANTI DEPRESSANT ACTIVITY OF CAESALPINIA PULCHERRIMA IN ANIMAL MODELS
Samreen
Paper Contents
Abstract
Caesalpinia pulcherrima belongs to the family fabaceae. Depressions are widespread psychiatric disorders affecting around 5% of the population. Furthermore, it is difficult to predict which patient will respond to any given treatment. In the traditional systems of medicine, many plants have been used to treat anxiety and depression for thousands of years. The present study was designed to evaluate the antidepressant activity of the alcoholic and aqueous extracts of Caesalpinia pulcherrima leaves in rodents. The antidepressant activity was tested by using forced swim test and Open Field Test. The results infer that reduced immobility time elicits antidepressant activity. It was concluded that alcoholic and aqueous extracts of Caesalpinia pulcherrima leaves having antidepressant activity. Alcoholic extract of Caesalpinia pulcherrima leaves showing more significant activity over the aqueous extract.
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