Paper Contents
Abstract
Few treatments for Alzheimer's disease, a major cause of cognitive loss globally, provide more than short-term symptom relief. Although they offer some limited advantages, cholinesterase inhibitors and other traditional treatments are unable to stop or reverse the disease's course. A fascinating possibility has been offered by recent studies: The class of drugs known as proton pump inhibitors (PPIs), which are typically used to treat gastrointestinal disorders including acid reflux and ulcers, may be a promising new treatment option for Alzheimer's disease. According to recent studies, PPIs may have neuroprotective qualities that could reduce the cognitive decline linked to Alzheimer's disease. This article examines the most recent clinical research on PPIspossible use in the treatment of Alzheimer's disease, explains the scientific mechanisms underlying these discoveries, and talks about the wider ramifications of these findings for future therapeutic approaches. We provide new treatment options and new hope to Alzheimer's patients and caregivers by repurposing an established class of medications.
Copyright
Copyright © 2025 Anchal Dhawan. This is an open access article distributed under the Creative Commons Attribution License.
