Seasonal Trends and Global Impact of Human Metapneumovirus: A Review of Current Research
Mr. Sanket Sanjay Amrutkar Sanket Sanjay Amrutkar
Paper Contents
Abstract
Human metapneumovirus (hMPV) is a significant respiratory pathogen affecting individuals across various age groups, particularly young children, immunocompromised individuals, and the elderly. Despite its discovery in 2001, hMPV remains underdiagnosed due to its clinical similarity to other respiratory viruses such as respiratory syncytial virus (RSV) and influenza. The virus exhibits seasonal patterns, with increased prevalence during winter and early spring in temperate regions, whereas tropical regions show more variable trends. hMPV is responsible for a considerable proportion of acute respiratory infections (ARIs), leading to hospitalizations and severe complications, especially in high-risk populations.This review explores the seasonal patterns, epidemiological trends, and global burden of hMPV, highlighting the latest advancements in diagnosis, treatment, and prevention strategies. Molecular diagnostic techniques such as polymerase chain reaction (PCR) have improved detection rates, yet challenges remain due to symptom overlap with other respiratory pathogens. Currently, there is no specific antiviral treatment, and management is largely supportive, emphasizing the need for effective vaccine development. Recent efforts in vaccine research and emerging antiviral therapies show promise in reducing disease burden. Understanding these trends is crucial for developing effective public health policies, optimizing surveillance systems, and mitigating future outbreaks through improved prevention and control measures.
Copyright
Copyright © 2025 Mr. Sanket Sanjay Amrutkar . This is an open access article distributed under the Creative Commons Attribution License.