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STUDY OF FORMULATION AND EVALUATION OF IBUPROFEN GEL BY USING CHICLE

Kusum Gurjar Gurjar

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Abstract

The Ibuprofen gel exhibited a well-defined homogeneous structure, demonstrating proficient drug loading capabilities. The pH of the gel formulations was measured and found to fall within the neutral range, signifying their compatibility with human skin. Furthermore, the viscosity assessments revealed that the formulation is appropriate for effective topical drug delivery. The drug content analysis yielded a concentration of 87.56, indicating a high efficiency in drug loading. This specific ibuprofen formulation was engineered as a prolonged-release gel for dermatological purposes, utilizing the natural polymer guar gum. The resultant gels displayed adequate homogeneity and texture. Notably, these formulated gels outperform commercially available alternatives, thereby establishing them as a viable option for the management of both localized and systemic inflammatory conditions.

Copyright

Copyright © 2025 Kusum Gurjar. This is an open access article distributed under the Creative Commons Attribution License.

Paper Details
Paper ID: IJPREMS50200002713
ISSN: 2321-9653
Publisher: ijprems
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